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BRCA1


1.9.2011

http://medicalxpress.com/news/2011-09-key-function-mutation-hereditary-breast.html
Key function of mutation in hereditary breast and ovarian cancer gene discovered
BRCA1 C-terminal (BRCT), BASC (BRCA1-associated genome surveillance complex)
1.9.2011

http://www.eurekalert.org/pub_releases/2011-09/vcu-kfo090111.php
Key function of mutation in hereditary breast and ovarian cancer gene discovered
BRCA1 C-terminal (BRCT), BASC (BRCA1-associated genome surveillance complex)
14.12.2011

http://medicalxpress.com/news/2011-12-scientists-brca1-cancer-gene-mutations.html
Scientists show how BRCA1 cancer gene mutations harm breast cells
TP53
28.10.2011

http://the-scientist.com/2011/10/27/brca1-further-elucidated/
BRCA1 Further Elucidated

11.10.2011

http://www.eurekalert.org/pub_releases/2011-10/uotm-ocp101011.php
Ovarian cancer patients survive longer with BRCA2 mutated in tumors
BRCA1 BRCA2
11.10.2011

http://medicalxpress.com/news/2011-10-ovarian-cancer-patients-survive-longer.html
Ovarian cancer patients survive longer with BRCA2 mutated in tumors
Ovarian-cancer-patients BRCA1 BRCA2
11.10.2011

http://medicalxpress.com/news/2011-10-brca2-genetic-mutation-survival-chemotherapy.html
BRCA2 genetic mutation associated with improved survival, chemotherapy response in ovarian cancer
BRCA1
23.3.2011

http://cancerres.aacrjournals.org/content/71/6/2360.short?rss=1
Histone Methyltransferase EZH2 Induces Akt-Dependent Genomic Instability and BRCA1 Inhibition in Breast Cancer
Akt-Dependent
18.11.2010

http://www.physorg.com/news/2010-11-parp-inhibitor-mk-anti-tumor-trial.html
PARP inhibitor, MK-4827, shows anti-tumor activity in first trial in humans
BRCA1 BRCA2
14.11.2007

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0001129
BRCA1: A Novel Prognostic Factor in Resected Non-Small-Cell Lung Cancer
BRCA1
29.5.2009

http://news.scotsman.com/scitech/Scientists-unlock-the-secrets-of.5309557.jp
Scientists unlock the secrets of gene that fights cancer
BRCA1 CtlP
25.12.2010

http://www.jci.org/articles/view/39447
Centrosomal Nlp is an oncogenic protein that is gene-amplified in human tumors and causes spontaneous tumorigenesis in transgenic mice
BRCA1 TUMOR BIOMARKER PROTEIN CANCERS OF OVARY
20.9.2010

http://www.eurekalert.org/pub_releases/2010-09/mc-fpr091510.php
4 possible risk factors for ovarian cancer found
BRCA1 SNPs
20.9.2010

http://www.eurekalert.org/pub_releases/2010-09/dumc-tsf091610.php
2 studies find new genetic links to ovarian cancer risk
BRCA1 BRCA2
27.4.2009

http://www.eurekalert.org/pub_releases/2007-04/mgh-msm041207.php
Molecular signature may identify cisplatin-sensitive breast tumors
cisplatin HER2 p73 p63 BRCA1
19.1.2008

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0001448
Yeast Screens Identify the RNA Polymerase II CTD and SPT5 as Relevant Targets of BRCA1 Interaction

23.11.2008

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0003695
Tumor BRCA1, RRM1 and RRM2 mRNA Expression Levels and Clinical Response to First-Line Gemcitabine plus Docetaxel in Non-Small-Cell Lung Cancer Patients

1.5.2008

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0002024
BRCA1 and BRCA2 Germline Mutations in Malaysian Women with Early-Onset Breast Cancer without a Family History

22.6.2008

http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1000080
BRCA1 and BRCA2 Missense Variants of High and Low Clinical Significance Influence Lymphoblastoid Cell Line Post-Irradiation Gene Expression

3.6.2010

http://www.eurekalert.org/pub_releases/2010-04/tum-ria042110.php
Researchers identify a new breast and ovarian cancer susceptibility gene
BRCA1 BRCA2 RAD51C
24.4.2010

http://www.wissenschaft.de/wissenschaft/news/310813.html
Genetische Veränderungen in Lymphknoten geben Hinweis auf Metastasenbildung
BRCA1 Her2neu
22.6.2008

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0002336
Analysis of the DNA Binding Activity of BRCA1 and Its Modulation by the Tumour Suppressor p53

18.12.2009

http://www.eurekalert.org/pub_releases/2009-12/nymc-rsl121809.php
Research suggests link between infertility, low egg reserve, and breast/ovarian cancer gene (BRCA1)
breast-cancer ovarian-cancer
1.9.2009

http://www.eurekalert.org/pub_releases/2009-08/uoha-sfu083109.php
Scientists from University of Hawaii at Manoa find genetic marker
Ovarian-cancer, BRCA1 BRCA2, BNC2 basonuclin-2
6.9.2008

http://www.issoonline.com/content/5/1/21
Contribution of BRCA1 germline mutation in patients with sporadic breast cancer

27.6.2008

http://news.bbc.co.uk/go/rss/-/1/hi/health/7470738.stm
Gene fuels deadly prostate cancer
BRCA2 BRCA1
2.8.2008

http://www.mskcc.org/mskcc/html/83923.cfm
Benefit of Cancer Prevention Surgery Differs Between Women with BRCA1 and BRCA2 Mutations

8.6.2008

http://www.biomedcentral.com/1471-2407/8/146
Analysis of large deletions in BRCA1, BRCA2 and PALB2 genes in Finnish breast and ovarian cancer families

24.5.2008

http://www.biomedcentral.com/1471-2407/8/140
Spectrum and characterisation of BRCA1 and BRCA2 deleterious mutations in high-risk Czech patients with breast and/or ovarian cancer

1.5.2008

http://idw-online.de/pages/de/news255806
Veränderungen an Gen könnten neue Erkenntnisse über Brustkrebs bringen
BRCA1
12.1.2008

http://www.celldiv.com/content/3/1/1
The ubiquitin E3 ligase activity of BRCA1 and its biological functions
BRCA1 basal-like breast cancer
2.4.2008

http://dx.doi.org/10.1038/ncb0408-377
BRCA1 and stem cells: tumour typecasting
cells breast cancers
18.2.2008

http://www.eurekalert.org/pub_releases/2008-02/mscc-boc020708.php
Benefit of cancer prevention surgery differs between women with BRCA1 and BRCA2 mutations
breast and ovarian cancer
13.12.2007

http://www.newswise.com/articles/view/535965/
How BRCA1 Mutations Cause Breast Cancer Revealed for First Time

13.12.2007

http://www.biologynews.net/archives/2007/12/09/new_study_reveals_for_first_time_how_brca1_mutations_cause_breast_cancer.html
New study reveals for first time how BRCA1 mutations cause breast cancer

13.12.2007

http://www.newswise.com/articles/view/535965/
How BRCA1 Mutations Cause Breast Cancer Revealed for First Time

11.4.2008

http://www.biomedcentral.com/1471-2407/8/96
Haplotype analysis of TP53 polymorphisms, Arg72Pro and Ins16, in BRCA1 and BRCA2 mutation carriers of French Canadian descent

11.4.2008

http://www.biomedcentral.com/1471-2407/8/90
Ovarian cancer risk in Polish BRCA1 mutation carriers is not associated with the prohibitin 3' untranslated region polymorphism

26.3.2008

http://www.innovations-report.de/html/berichte/medizin_gesundheit/bericht-106067.html
Neue Hoffnung für Trägerinnen eines Risikogens für Brustkrebs
BRCA1 BRCA2 Risiko Gen
10.3.2008

http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.0040020
Getting Started in Text Mining
automatisch-Assoziationen-lernen, BRCA1, breast cancer
3.3.2008

http://www.biomedcentral.com/1471-2407/8/59
Rapid detection of carriers with BRCA1 and BRCA2 mutations using high resolution melting analysis

18.2.2008

http://www.eurekalert.org/pub_releases/2008-02/fhcr-srw020508.php
Study reveals why certain ovarian cancers develop resistance to platinum-based chemotherapy
platinum BRCA1 BRCA2 DNA-repair,
18.2.2008

http://www.innovations-report.de/html/berichte/biowissenschaften_chemie/bericht-103194.html
Benefit of cancer prevention surgery differs between women with BRCA1 and BRCA2 mutations

18.2.2008

http://www.newswise.com/articles/view/537596/?sc=rsmn
Benefit of Cancer Prevention Surgery Differs Between Women with BRCA1 and BRCA2 Mutations

8.2.2008

http://www.eurekalert.org/pub_releases/2008-01/uomh-bml013108.php
BRCA1 mutation linked to breast cancer stem cells

27.1.2008

http://www.eurekalert.org/pub_releases/2007-06/dci-sal060807.php
Screening approach leads to discovery of gene linked to breast cancer
BRCA1 BRCA2 Ras IKBKE
19.1.2008

http://www.news-medical.net/?id=34435
New clues about BRCA1 role in breast cancer

19.1.2008

http://www.brightsurf.com/news/headlines/35323/New_pathway_provides_more_clues_about_BRCA1_role_in_breast_cancer.html
New pathway provides more clues about BRCA1 role in breast cancer

19.1.2008

http://www.eurekalert.org/pub_releases/2008-01/dumc-npp011008.php
New pathway provides more clues about BRCA1 role in breast cancer

12.1.2008

http://www.eurekalert.org/pub_releases/2008-01/mscc-bcr010208.php
Breast cancer risk varies among women who are carriers of BRCA1 and BRCA2 gene mutations

12.1.2008

http://www.eurekalert.org/pub_releases/2008-01/jaaj-bcr010308.php
Breast cancer risk varies significantly among BRCA1 and BRCA2 carriers

3.1.2008

http://jama.ama-assn.org/cgi/content/short/298/24/2869?rss=1
ORIGINAL CONTRIBUTION: Prevalence of Pathogenic BRCA1 Mutation Carriers in 5 US Racial/Ethnic Groups

3.1.2008

http://www.mercurynews.com/ci_7809760?source=rss
Stanford study: Gene flaw in breast cancer has ethnic link
BRCA1 mutation
13.12.2007

http://www.physorg.com/news116429642.html
New study reveals for first time how BRCA1 mutations cause breast cancer

13.12.2007

http://www.aerzteblatt.de/v4/news/news.asp?id=30740
Medizin: Wie BRCA1 Brustkrebs erzeugt

13.12.2007

http://www.eurekalert.org/pub_releases/2007-12/cumc-nsr120507.php
New study reveals for first time how BRCA1 mutations cause breast cancer

21.11.2007

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0001129
BRCA1: A Novel Prognostic Factor in Resected Non-Small-Cell Lung Cancer
BRCA1
15.10.2007

http://www.eurekalert.org/pub_releases/2007-10/uocm-edm101107.php
Enhanced DNA-repair mechanism can cause breast cancer
BRCA1 DNA-repair
4.9.2007

http://www.sciencedaily.com/releases/2007/08/070831123432.htm
Breast Cancer Risk: Breast Density Gene Located
BRCA1 BRCA2 Risk
11.4.2007

http://www.eurekalert.org/pub_releases/2007-02/jhu-cth021207.php
Computer tool helps pinpoint risky gene mutations
BRCA1 Gen
26.2.2007

http://www.eurekalert.org/pub_releases/2007-02/aof-geb020807.php
Gene elevating breast cancer risk also causes prostate cancer
BRCA1 BRCA2 PALB2
26.12.2006

http://www.eurekalert.org/pub_releases/2006-09/jaaj-pmh092106.php
Prediction models help identify increased risk of gene mutation linked with colorectal cancer
Lynch syndrome (also called hereditary nonpolyposis colorectal cancer) BRCA1 BRCA2
2.4.2005

http://www.innovations-report.de/html/berichte/biowissenschaften_chemie/bericht-42267.html
BRCA1 causes ovarian cancer through indirect, biochemical route
Eierstockkrebs, Brustkrebs-Gen BRCA1
13.11.2006

http://science.orf.at/science/news/145929
Forscher: Weiteres Brustkrebs-Gen entdeckt
BRIP1 Brustkrebs Gen, BRCA1, BRCA2
9.9.2006

http://www.eurekalert.org/pub_releases/2006-08/nhgr-nfo081406.php
New findings offer more complete view of breast cancer gene mutations in US population
BRCA1 BRCA2 mutations
12.8.2006

http://www.biologynews.net/archives/2006/07/18/study_identifies_new_role_for_breast_cancer_susceptibility_gene.html
Study identifies new role for breast cancer susceptibility gene
BRCA1 ANG1
9.8.2006

http://www.eurekalert.org/pub_releases/2006-08/hms-hfd080306.php
Hunt for DNA amplified in cancers uncovers important target gene
YAP Gen, BRCA1 p53 Myc
9.8.2006

http://www.eurekalert.org/pub_releases/2006-07/ra-bsc071806.php
Breast stem cells have features similar to 'basal' tumors
BRCA1 Gen
2.7.2006

http://www.abc.net.au/science/news/stories/s1668364.htm
New gene ups breast cancer risk to 80%
BARD1 BRCA1 BRCA2
21.4.2006

http://www.eurekalert.org/pub_releases/2006-04/bcom-mtm041706.php
Mouse to man: The story of chromosomes
Chromosom Maus Mensch 17 11 BRCA1 NF1 NEUROFIBROMATOSIS TP53
17.2.2006

http://www.eurekalert.org/pub_releases/2006-02/gumc-vcc020906.php
Veggies contain chemicals that boost DNA repair and protect against cancer
repair protect cancer Veggies BRCA1 BRCA2 Blumenkohl, Kohl, Brokkoli
16.4.2005

http://www.netzeitung.de/spezial/gentechnik/334015.html
Medikament sabotiert Brustkrebs-Zellen
sabotieren Brustkrebs Zelle, BRCA1 BRCA2, Poly-ADP-Ribose-Polymerase PARP